| First Lady |
Mamie Eisenhower |
| Vice President |
Richard Nixon (1953–1961) |
| Secretary of State |
John Foster Dulles (1953–1959) |
| Secretary of State |
Christian A. Herter (1959–1961) |
| Secretary of Defense |
Charles E. Wilson (1953–1957) |
| Secretary of Defense |
Neil H. McElroy (1957–1959) |
| Secretary of Defense |
Thomas S. Gates Jr. (1959–1961) |
| Secretary of the Interior |
Douglas J. McKay (1953–1956) |
| Secretary of the Interior |
Frederick A. Seaton (1956–1961) |
| Attorney General |
Herbert Brownell, Jr. (1953–1957) |
| Attorney General |
William P. Rogers (1957–1961) |
| Postmaster General |
Arthur E. Summerfield (1953–1961) |
| Secretary of the Treasury |
George M. Humphrey (1953–1957) |
| Secretary of the Treasury |
Robert B. Anderson (1957–1961) |
| Secretary of Labor |
Martin P. Durkin (1953) |
| Secretary of Labor |
James P. Mitchell (1953–1961) |
| Secretary of Commerce |
Sinclair Weeks (1953–1958) |
| Secretary of Commerce |
Lewis Strauss (1958–1959) |
| Secretary of Commerce |
Frederick H. Mueller (1959–1961) |
| Secretary of Agriculture |
Ezra Taft Benson (1953–1961) |
| Secretary of Health, Education, and Welfare |
Oveta Culp Hobby (1953–1955) |
| Secretary of Health, Education, and Welfare |
Marion B. Folsom (1955–1958) |
| Secretary of Health, Education, and Welfare |
Arthur Flemming (1958–1961) |