James A. Garfield - Administration
| First Lady | Lucretia Garfield |
| Vice President | Chester Arthur (1881) |
| Secretary of State | James G. Blaine (1881) |
| Secretary of the Interior | Samuel J. Kirkwood (1881) |
| Attorney General | Isaac Wayne MacVeagh (1881) |
| Postmaster General | Thomas L. James (1881) |
| Secretary of the Treasury | William Windom (1881) |
| Secretary of the Navy | William H. Hunt (1881) |
| Secretary of War | Robert Todd Lincoln (1881) |