John Quincy Adams - Administration
| First Lady | Louisa Adams |
| Vice President | John C. Calhoun (1825-1829) |
| Secretary of State | Henry Clay (1825–1829) |
| Attorney General | William Wirt (1825–1829) |
| Postmaster General | John McLean (1825–1829) |
| Secretary of the Treasury | Richard Rush (1825–1829) |
| Secretary of the Navy | Samuel L. Southard (1825–1829) |
| Secretary of War | James Barbour (1825–1828) |
| Secretary of War | Peter B. Porter (1828–1829) |