James K. Polk - Administration
| First Lady | Sarah Polk |
| Vice President | George M. Dallas (1845–1849) |
| Secretary of State | James Buchanan (1845–1849) |
| Attorney General | Isaac Toucey (1848–1849) |
| Attorney General | Nathan Clifford (1846–1848) |
| Attorney General | John Y. Mason (1845–1846) |
| Postmaster General | Cave Johnson (1845–1849) |
| Secretary of the Treasury | Robert J. Walker (1845–1849) |
| Secretary of the Navy | John Y. Mason (1846–1849) |
| Secretary of the Navy | George Bancroft (1845–1846) |
| Secretary of War | William L. Marcy (1845–1849) |