| First Lady |
Anna Eleanor Roosevelt |
| Vice President |
John N. Garner (1933–1941) |
| Vice President |
Henry A. Wallace (1941–1945) |
| Vice President |
Harry Truman (1945) |
| Secretary of State |
Cordell Hull (1933–1944) |
| Secretary of State |
Edward R. Stettinius Jr. (1944–1945) |
| Secretary of the Interior |
Harold L. Ickes (1933–1945) |
| Attorney General |
Homer S. Cummings (1933–1939) |
| Attorney General |
Frank Murphy (1939–1940) |
| Attorney General |
Robert H. Jackson (1940–1941) |
| Attorney General |
Francis B. Biddle (1941–1945) |
| Postmaster General |
Frank C. Walker (1940–1945) |
| Postmaster General |
James A. Farley (1933–1940) |
| Secretary of the Treasury |
William H. Woodin (1933) |
| Secretary of the Treasury |
Henry Morgenthau Jr. (1934–1945) |
| Secretary of Labor |
Frances Perkins (1933–1945) |
| Secretary of Commerce |
Jesse H. Jones (1940–1945) |
| Secretary of Commerce |
Daniel C. Roper (1933–1938) |
| Secretary of Commerce |
Henry A. Wallace (1945) |
| Secretary of Commerce |
Harry L. Hopkins (1938–1940) |
| Secretary of Agriculture |
Henry A. Wallace (1933–1940) |
| Secretary of Agriculture |
Claude R. Wickard (1940–1945) |
| Secretary of the Navy |
Claude A. Swanson (1933–1939) |
| Secretary of the Navy |
Charles Edison (1940) |
| Secretary of the Navy |
Frank Knox (1940–1944) |
| Secretary of the Navy |
James V. Forrestal (1944–1945) |
| Secretary of War |
George H. Dern (1933–1936) |
| Secretary of War |
Harry H. Woodring (1936–1940) |
| Secretary of War |
Henry L. Stimson (1940–1945) |